MSI Complete utilizes a MSI protocol which consists of eight markers – four of the gold standard markers, plus four novel markers. It has been hypothesized that these eight markers offer greater sensitivity for microsatellite instability (MSI) detection in cancers where the results are otherwise inconclusive or ambiguous.
The MSI Protocol is designed to provide physicians with a functional, molecular measurement of the level of DNA mismatch repair deficiency demonstrated within a patient’s tumor. MSI-high (MSI-H) could be an indication of immunotherapy response in colorectal cancer.
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