Precision Medicine

Technological advances combined with an improved understanding of the genetic basis of cancer has allowed individualized profiling that is revolutionizing personalized medicine and cancer treatment.

With minimal-volumes of blood, CIRCULOGENE’s patented technology utilizes next-generation sequencing (NGS) to monitor known tumor mutations (approximately 3,000) in the following, scientifically established cancer-associated genes.

Click here to read descriptions of individual genes.

ABL1
AKT1
ALK
APC
ATM
BRAF
CDH1
CDKN2A
CSF1R
CTNNB1
EGFR
ERBB2
ERBB4
EZH2
FBXW7
FGFR1
FGFR2

FGFR3
FLT3
GNA11
GNAQ
GNAS
HNF1A
HRAS
IDH1
IDH2
JAK2
JAK3
KDR
KIT
KRAS
MET
MLH1
MPL

NOTCH1
NPM1
NRAS
PDGFRA
PIK3CA
PTEN
PTPN11
RB1
RET
SMAD4
SMARCB1
SMO
SRC
STK11
TP53
VHL

CIRCULO Colorectal
BRAF
NRAS
PIK3CA
KRAS

CIRCULO Gastric
APC
KRAS
BRAF
PIK3CA

CIRCULO Prostate
TP53
PTEN
KRAS
PIK3CA

CIRCULO GIST
KIT
PDGFRA
BRAF

CIRCULO Hematological
FLT3
NPM1
JAK2
ABL1

CIRCULO Head and Neck
TP53
PIK3CA
NOTCH1
CDKN2A

CIRCULO Thyroid
KRAS
BRAF
RET
NRAS

CIRCULO Breast
PIK3CA
ERBB2
AKT1
PTEN

CIRCULO Ovarian
KRAS
BRAF
PIK3CA
PTEN

CIRCULO Gallbladder
TP53
PIK3CA
KRAS
BRAF

CIRCULO Melanoma
BRAF
NRAS
KIT

CIRCULO Pancreatic
KRAS
CDKN2A
TP53

CIRCULO Bladder
TP53
PTEN
RB1
PIK3CA

Comprehensive Lung Panel
EGFR
KRAS
ALK
PIK3CA
BRAF
ALK Gene Fusion (RNA)
ROS1 Gene Fusion (RNA)
PD-L1 Expression

RNA TEST MENU
ALK Gene Fusion
ROS1 Gene Fusion

IMMUNOTHERAPY TEST MENU
MSI-H
PD-L1 Expression